1 | #!/usr/bin/env python
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2 | #Dan Blankenberg
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3 |
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4 | import sys, os
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5 |
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6 | assert sys.version_info[:2] >= ( 2, 4 )
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7 |
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8 | def __main__():
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9 | base_dir = os.path.join( os.getcwd(), "bacteria" )
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10 | try:
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11 | base_dir = sys.argv[1]
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12 | except:
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13 | print "using default base_dir:", base_dir
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14 |
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15 | loc_out = os.path.join( base_dir, "seq.loc" )
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16 | try:
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17 | loc_out = os.path.join( base_dir, sys.argv[2] )
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18 | except:
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19 | print "using default seq.loc:", loc_out
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20 |
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21 |
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22 |
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23 | organisms = {}
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24 |
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25 | loc_out = open( loc_out, 'wb' )
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26 |
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27 | for result in os.walk( base_dir ):
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28 | this_base_dir, sub_dirs, files = result
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29 | for file in files:
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30 | if file[-5:] == ".info":
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31 | dict = {}
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32 | info_file = open( os.path.join( this_base_dir, file ), 'r' )
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33 | info = info_file.readlines()
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34 | info_file.close()
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35 | for line in info:
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36 | fields = line.replace( "\n", "" ).split( "=" )
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37 | dict[fields[0]]="=".join(fields[1:])
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38 | if 'genome project id' in dict.keys():
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39 | name = dict['genome project id']
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40 | if 'build' in dict.keys():
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41 | name = dict['build']
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42 | if name not in organisms.keys():
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43 | organisms[name] = {'chrs':{}, 'base_dir':this_base_dir}
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44 | for key in dict.keys():
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45 | organisms[name][key] = dict[key]
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46 | else:
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47 | if dict['organism'] not in organisms.keys():
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48 | organisms[dict['organism']] = {'chrs':{},'base_dir':this_base_dir}
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49 | organisms[dict['organism']]['chrs'][dict['chromosome']] = dict
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50 |
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51 |
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52 | for org in organisms:
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53 | org = organisms[org]
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54 | try:
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55 | build = org['genome project id']
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56 | except: continue
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57 | if 'build' in org:
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58 | build = org['build']
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59 |
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60 | seq_path = os.path.join( org['base_dir'], "seq" )
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61 |
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62 | #create seq dir, if exists go to next org
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63 | ##TODO: add better checking, i.e. for updating
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64 | try:
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65 | os.mkdir( seq_path )
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66 | except:
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67 | print "Skipping", build
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68 | #continue
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69 |
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70 | loc_out.write( "seq %s %s\n" % ( build, seq_path ) )
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71 |
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72 | #print org info
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73 |
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74 | for chr in org['chrs']:
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75 | chr = org['chrs'][chr]
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76 |
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77 | fasta_file = os.path.join( org['base_dir'], "%s.fna" % chr['chromosome'] )
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78 | nib_out_file = os.path.join( seq_path, "%s.nib "% chr['chromosome'] )
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79 | #create nibs using faToNib binary
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80 | #TODO: when bx supports writing nib, use it here instead
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81 | command = "faToNib %s %s" % ( fasta_file, nib_out_file )
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82 | os.system( command )
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83 |
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84 | loc_out.close()
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85 |
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86 |
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87 |
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88 | if __name__ == "__main__": __main__()
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