1 | ## Rgenetics: http://rgenetics.org Galaxy Tools rgLDIndep.py started 09/05/2010 21:23:42 |
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2 | ## Rgenetics January 4 2010: http://rgenetics.org Galaxy Tools rgLDIndep.py Plink pruneLD runner |
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3 | ## ldindep now executing plink --noweb --bfile /share/shared/galaxy/test-data/tinywga --indep-pairwise 10000 5000 0.1 --out /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1 --mind 1 --geno 1 --maf 0 --hwe 0 --me 1 1 |
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4 | |
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5 | @----------------------------------------------------------@ |
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6 | | PLINK! | v1.07 | 10/Aug/2009 | |
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7 | |----------------------------------------------------------| |
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8 | | (C) 2009 Shaun Purcell, GNU General Public License, v2 | |
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9 | |----------------------------------------------------------| |
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10 | | For documentation, citation & bug-report instructions: | |
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11 | | http://pngu.mgh.harvard.edu/purcell/plink/ | |
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12 | @----------------------------------------------------------@ |
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13 | |
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14 | Skipping web check... [ --noweb ] |
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15 | Writing this text to log file [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.log ] |
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16 | Analysis started: Sun May 9 21:23:42 2010 |
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17 | |
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18 | Options in effect: |
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19 | --noweb |
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20 | --bfile /share/shared/galaxy/test-data/tinywga |
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21 | --indep-pairwise 10000 5000 0.1 |
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22 | --out /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1 |
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23 | --mind 1 |
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24 | --geno 1 |
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25 | --maf 0 |
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26 | --hwe 0 |
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27 | --me 1 1 |
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28 | |
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29 | Reading map (extended format) from [ /share/shared/galaxy/test-data/tinywga.bim ] |
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30 | 25 markers to be included from [ /share/shared/galaxy/test-data/tinywga.bim ] |
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31 | Reading pedigree information from [ /share/shared/galaxy/test-data/tinywga.fam ] |
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32 | 40 individuals read from [ /share/shared/galaxy/test-data/tinywga.fam ] |
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33 | 40 individuals with nonmissing phenotypes |
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34 | Assuming a disease phenotype (1=unaff, 2=aff, 0=miss) |
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35 | Missing phenotype value is also -9 |
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36 | 10 cases, 30 controls and 0 missing |
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37 | 21 males, 19 females, and 0 of unspecified sex |
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38 | Reading genotype bitfile from [ /share/shared/galaxy/test-data/tinywga.bed ] |
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39 | Detected that binary PED file is v1.00 SNP-major mode |
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40 | Before frequency and genotyping pruning, there are 25 SNPs |
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41 | 27 founders and 13 non-founders found |
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42 | 0 markers to be excluded based on HWE test ( p <= 0 ) |
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43 | 0 markers failed HWE test in cases |
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44 | 0 markers failed HWE test in controls |
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45 | Total genotyping rate in remaining individuals is 0.995 |
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46 | 0 SNPs failed missingness test ( GENO > 1 ) |
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47 | 0 SNPs failed frequency test ( MAF < 0 ) |
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48 | After frequency and genotyping pruning, there are 25 SNPs |
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49 | After filtering, 10 cases, 30 controls and 0 missing |
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50 | After filtering, 21 males, 19 females, and 0 of unspecified sex |
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51 | 14 nuclear families, 1 founder singletons found |
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52 | 13 non-founders with 2 parents in 13 nuclear families |
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53 | 0 non-founders without 2 parents in 0 nuclear families |
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54 | 10 affected offspring trios |
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55 | 0 phenotypically discordant parent pairs found |
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56 | Converting data to Individual-major format |
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57 | Filtering SNPs/families for Mendel Error rates above 1, 1 |
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58 | 0 Mendel errors detected in total |
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59 | 0 families ( 0 individuals ) removed due to Mendel errors |
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60 | 0 markers removed due to Mendel errors, 25 remaining |
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61 | Converting data to SNP-major format |
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62 | Performing LD-based pruning... |
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63 | Writing pruned-in SNPs to [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.prune.in ] |
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64 | Writing pruned-out SNPs to [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.prune.out ] |
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65 | Scanning from chromosome 22 to 22 |
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66 | |
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67 | Scan region on chromosome 22 from [ rs2283802 ] to [ rs4822375 ] |
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68 | For chromosome 22, 22 SNPs pruned out, 3 remaining |
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69 | |
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70 | Analysis finished: Sun May 9 21:23:42 2010 |
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71 | |
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72 | |
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73 | ## ldindep now executing plink --noweb --bfile /share/shared/galaxy/test-data/tinywga --extract /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.prune.in --make-bed --out /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1 |
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74 | |
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75 | @----------------------------------------------------------@ |
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76 | | PLINK! | v1.07 | 10/Aug/2009 | |
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77 | |----------------------------------------------------------| |
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78 | | (C) 2009 Shaun Purcell, GNU General Public License, v2 | |
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79 | |----------------------------------------------------------| |
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80 | | For documentation, citation & bug-report instructions: | |
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81 | | http://pngu.mgh.harvard.edu/purcell/plink/ | |
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82 | @----------------------------------------------------------@ |
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83 | |
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84 | Skipping web check... [ --noweb ] |
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85 | Writing this text to log file [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.log ] |
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86 | Analysis started: Sun May 9 21:23:42 2010 |
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87 | |
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88 | Options in effect: |
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89 | --noweb |
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90 | --bfile /share/shared/galaxy/test-data/tinywga |
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91 | --extract /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.prune.in |
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92 | --make-bed |
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93 | --out /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1 |
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94 | |
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95 | Reading map (extended format) from [ /share/shared/galaxy/test-data/tinywga.bim ] |
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96 | 25 markers to be included from [ /share/shared/galaxy/test-data/tinywga.bim ] |
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97 | Reading pedigree information from [ /share/shared/galaxy/test-data/tinywga.fam ] |
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98 | 40 individuals read from [ /share/shared/galaxy/test-data/tinywga.fam ] |
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99 | 40 individuals with nonmissing phenotypes |
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100 | Assuming a disease phenotype (1=unaff, 2=aff, 0=miss) |
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101 | Missing phenotype value is also -9 |
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102 | 10 cases, 30 controls and 0 missing |
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103 | 21 males, 19 females, and 0 of unspecified sex |
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104 | Reading genotype bitfile from [ /share/shared/galaxy/test-data/tinywga.bed ] |
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105 | Detected that binary PED file is v1.00 SNP-major mode |
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106 | Reading list of SNPs to extract [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.prune.in ] ... 3 read |
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107 | Before frequency and genotyping pruning, there are 3 SNPs |
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108 | 27 founders and 13 non-founders found |
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109 | Total genotyping rate in remaining individuals is 1 |
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110 | 0 SNPs failed missingness test ( GENO > 1 ) |
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111 | 0 SNPs failed frequency test ( MAF < 0 ) |
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112 | After frequency and genotyping pruning, there are 3 SNPs |
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113 | After filtering, 10 cases, 30 controls and 0 missing |
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114 | After filtering, 21 males, 19 females, and 0 of unspecified sex |
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115 | Writing pedigree information to [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.fam ] |
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116 | Writing map (extended format) information to [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.bim ] |
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117 | Writing genotype bitfile to [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.bed ] |
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118 | Using (default) SNP-major mode |
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119 | |
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120 | Analysis finished: Sun May 9 21:23:42 2010 |
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121 | |
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122 | |
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123 | ## ldindep now executing plink --noweb --bfile /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1 --recode --out /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1 |
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124 | |
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125 | @----------------------------------------------------------@ |
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126 | | PLINK! | v1.07 | 10/Aug/2009 | |
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127 | |----------------------------------------------------------| |
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128 | | (C) 2009 Shaun Purcell, GNU General Public License, v2 | |
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129 | |----------------------------------------------------------| |
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130 | | For documentation, citation & bug-report instructions: | |
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131 | | http://pngu.mgh.harvard.edu/purcell/plink/ | |
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132 | @----------------------------------------------------------@ |
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133 | |
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134 | Skipping web check... [ --noweb ] |
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135 | Writing this text to log file [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.log ] |
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136 | Analysis started: Sun May 9 21:23:42 2010 |
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137 | |
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138 | Options in effect: |
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139 | --noweb |
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140 | --bfile /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1 |
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141 | --recode |
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142 | --out /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1 |
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143 | |
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144 | Reading map (extended format) from [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.bim ] |
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145 | 3 markers to be included from [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.bim ] |
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146 | Reading pedigree information from [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.fam ] |
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147 | 40 individuals read from [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.fam ] |
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148 | 40 individuals with nonmissing phenotypes |
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149 | Assuming a disease phenotype (1=unaff, 2=aff, 0=miss) |
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150 | Missing phenotype value is also -9 |
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151 | 10 cases, 30 controls and 0 missing |
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152 | 21 males, 19 females, and 0 of unspecified sex |
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153 | Reading genotype bitfile from [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.bed ] |
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154 | Detected that binary PED file is v1.00 SNP-major mode |
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155 | Before frequency and genotyping pruning, there are 3 SNPs |
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156 | 27 founders and 13 non-founders found |
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157 | Total genotyping rate in remaining individuals is 1 |
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158 | 0 SNPs failed missingness test ( GENO > 1 ) |
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159 | 0 SNPs failed frequency test ( MAF < 0 ) |
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160 | After frequency and genotyping pruning, there are 3 SNPs |
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161 | After filtering, 10 cases, 30 controls and 0 missing |
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162 | After filtering, 21 males, 19 females, and 0 of unspecified sex |
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163 | Writing recoded ped file to [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.ped ] |
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164 | Writing new map file to [ /share/shared/galaxy/test-data/rgtestouts/rgLDIndep/rgLDIndeptest1.map ] |
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165 | |
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166 | Analysis finished: Sun May 9 21:23:42 2010 |
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167 | |
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168 | |
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169 | |
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