1 | <tool id="hgv_linkToGProfile" name="g:Profiler" version="1.0.0"> |
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2 | <description>tools for functional profiling of gene lists</description> |
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3 | |
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4 | <command interpreter="perl"> |
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5 | linkToGProfile.pl $input $numerical_column $type $out_file1 |
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6 | </command> |
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7 | |
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8 | <inputs> |
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9 | <param name="input" type="data" format="tabular" label="Dataset" /> |
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10 | <param name="numerical_column" type="data_column" data_ref="input" numerical="True" label="Column with identifiers" /> |
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11 | <param name="type" label="Identifier type" type="select"> |
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12 | <option value="ENTREZGENE_ACC" selected="true">Entrez Gene Acc</option> |
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13 | <option value="MIM_MORBID">OMIM Morbid Map</option> |
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14 | <option value="MIM_GENE">OMIM Gene ID</option> |
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15 | <option value="AFFY_HUGENE_1_0_ST_V1">AFFY_HUGENE_1_0_ST_V1</option> |
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16 | <option value="HGNC_AUTOMATIC_GENE_ACC">HGNC_AUTOMATIC_GENE_ACC</option> |
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17 | <option value="HGNC_MB001_ACC">HGNC_MB001_ACC</option> |
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18 | <option value="HGNC_ACC">HGNC_ACC</option> |
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19 | <option value="WIKIGENE_ACC">WIKIGENE_ACC</option> |
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20 | <option value="DBASS5_ACC">DBASS5_ACC</option> |
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21 | <option value="ILLUMINA_HUMANWG_6_V1">ILLUMINA_HUMANWG_6_V1</option> |
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22 | <option value="AFFY_HUEX_1_0_ST_V2">AFFY_HUEX_1_0_ST_V2</option> |
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23 | <option value="DBASS3_ACC">DBASS3_ACC</option> |
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24 | </param> |
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25 | </inputs> |
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26 | |
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27 | <outputs> |
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28 | <data format="html" name="out_file1" /> |
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29 | </outputs> |
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30 | |
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31 | <tests> |
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32 | <test> |
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33 | <param name="input" ftype="tabular" value="linkToGProfile.tabular" /> |
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34 | <param name="numerical_column" value="2" /> |
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35 | <param name="type" value="ENTREZGENE_ACC" /> |
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36 | <output name="out_file1" file="linkToGProfile_1.out" /> |
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37 | </test> |
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38 | </tests> |
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39 | |
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40 | <help> |
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41 | **Dataset formats** |
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42 | |
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43 | The input dataset is tabular_ with a column of identifiers. |
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44 | The output dataset is html_ with a link to g:Profiler. |
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45 | (`Dataset missing?`_) |
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46 | |
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47 | .. _tabular: ./static/formatHelp.html#tab |
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48 | .. _html: ./static/formatHelp.html#html |
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49 | .. _Dataset missing?: ./static/formatHelp.html |
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50 | |
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51 | ----- |
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52 | |
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53 | **What it does** |
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54 | |
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55 | This tool creates a link to the g:GOSt tool (Gene Group Functional |
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56 | Profiling), which is part of the g:Profiler site at the University |
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57 | of Tartu in Estonia. g:GOSt retrieves the most significant Gene |
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58 | Ontology (GO) terms, KEGG and REACTOME pathways, and TRANSFAC motifs |
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59 | for a user-specified group of genes, proteins, or microarray probes. |
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60 | g:GOSt also allows analysis of ranked or ordered lists of genes, |
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61 | visual browsing of GO graph structure, interactive visualization of |
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62 | retrieved results, and many other features. Multiple testing |
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63 | corrections are applied to extract only statistically important |
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64 | results. |
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65 | |
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66 | The g:GOSt form is pre-filled with gene, protein, or microarray probe |
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67 | IDs from the selected column of a tabular Galaxy dataset. To follow |
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68 | the created link, click on the eye icon when the Galaxy tool has |
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69 | finished running. Once at the g:Profiler site, scroll down to see |
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70 | the g:GOSt results. You can also adjust the options in the g:GOSt |
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71 | form to your liking, or use the row of links between the form and |
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72 | the results to run other g:Profiler tools using the same list of IDs. |
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73 | |
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74 | ----- |
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75 | |
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76 | **Reference** |
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77 | |
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78 | Reimand J, Kull M, Peterson H, Hansen J, Vilo J. (2007) g:Profiler -- a web-based |
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79 | toolset for functional profiling of gene lists from large-scale experiments. |
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80 | Nucleic Acids Res. 35(Web Server issue):W193-200. Epub 2007 May 3. |
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81 | |
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82 | </help> |
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83 | </tool> |
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