1 | #!/usr/bin/env python |
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2 | |
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3 | """ |
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4 | Read a maf and split blocks by unique species combinations |
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5 | """ |
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6 | import sys |
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7 | from galaxy import eggs |
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8 | import pkg_resources; pkg_resources.require( "bx-python" ) |
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9 | from bx.align import maf |
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10 | from galaxy.tools.util import maf_utilities |
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11 | from galaxy.util import string_as_bool |
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12 | |
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13 | assert sys.version_info[:2] >= ( 2, 4 ) |
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14 | |
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15 | def __main__(): |
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16 | try: |
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17 | maf_reader = maf.Reader( open( sys.argv[1] ) ) |
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18 | except Exception, e: |
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19 | maf_utilities.tool_fail( "Error opening MAF: %s" % e ) |
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20 | try: |
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21 | out = maf.Writer( open( sys.argv[2], "w") ) |
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22 | except Exception, e: |
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23 | maf_utilities.tool_fail( "Error opening file for output: %s" % e ) |
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24 | try: |
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25 | collapse_columns = string_as_bool( sys.argv[3] ) |
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26 | except Exception, e: |
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27 | maf_utilities.tool_fail( "Error determining collapse columns value: %s" % e ) |
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28 | |
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29 | start_count = 0 |
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30 | end_count = 0 |
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31 | for start_count, start_block in enumerate( maf_reader ): |
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32 | for block in maf_utilities.iter_blocks_split_by_species( start_block ): |
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33 | if collapse_columns: |
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34 | block.remove_all_gap_columns() |
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35 | out.write( block ) |
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36 | end_count += 1 |
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37 | out.close() |
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38 | |
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39 | if end_count: |
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40 | print "%i alignment blocks created from %i original blocks." % ( end_count, start_count + 1 ) |
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41 | else: |
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42 | print "No alignment blocks were created." |
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43 | |
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44 | if __name__ == "__main__": __main__() |
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