| 1 | <tool id="rgGTOOL1" name="Converter"> | 
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| 2 | <code file="listFiles.py"/> | 
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| 3 | <code file="rgGTOOL_code.py"/> | 
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| 4 |  | 
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| 5 | <description>from linkage format to SNPTEST Marchini files</description> | 
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| 6 |  | 
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| 7 | <command interpreter="python"> | 
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| 8 | rgGTOOL.py $i $o $discrete $logf $outdir | 
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| 9 | </command> | 
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| 10 |  | 
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| 11 | <inputs> | 
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| 12 | <param name="i"  type="select" label="Genotype file" dynamic_options="get_lib_pedfiles()" /> | 
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| 13 | <param name="discrete" type="select" label="Make Case/Control based on affection 2/1"> | 
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| 14 | <option selected="yes" value="1">Discrete</option> | 
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| 15 | <option value="0">Continuous</option> | 
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| 16 | </param> | 
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| 17 | <param name="o" type="text" label="Output Marchini format name" value="Marchini"/> | 
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| 18 | <param name="outdir" type="hidden" value="/usr/local/galaxy/data/rg/snptest" /> | 
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| 19 | </inputs> | 
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| 20 |  | 
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| 21 | <outputs> | 
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| 22 | <data format="txt" name="logf"  /> | 
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| 23 | </outputs> | 
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| 24 | <help> | 
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| 25 |  | 
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| 26 |  | 
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| 27 | **Syntax** | 
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| 28 |  | 
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| 29 | - **Genotype file** is the input linkage format pedigree and corresponding map file | 
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| 30 | - **Discrete** is the type of phenotype in the affection column | 
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| 31 | - **Output name** is the file name (.gen and .sample will be added) for the new SNPTEST compatible file | 
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| 32 |  | 
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| 33 | **Note on Discrete** | 
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| 34 | See GTOOL_ documentation link below for more details. Briefly, if | 
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| 35 | your linkage format pedigree file has 1/2 in column 6 for control/case respectively, setting this to Yes will create two | 
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| 36 | complete sets of output files distinguished by 1 and 2 respectively. otherwise, affection status is assumed to contain a | 
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| 37 | continuous phenotype and a single output set is produced | 
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| 38 |  | 
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| 39 |  | 
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| 40 | **Summary** | 
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| 41 |  | 
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| 42 | Code used here from Jonathon Marchini's group - see documentation at GTOOL_. | 
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| 43 |  | 
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| 44 | .. _GTOOL: http://www.stats.ox.ac.uk/~marchini/software/gwas/gtool.html | 
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| 45 |  | 
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| 46 | ----- | 
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| 47 |  | 
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| 48 | **Attribution** | 
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| 49 | Originally designed and written for the Rgenetics | 
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| 50 | series of Galaxy tools by ross lazarus (ross.lazarus@gmail.com), who didn't write GTOOL_ | 
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| 51 | but wishes he had. | 
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| 52 |  | 
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| 53 | </help> | 
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| 54 | </tool> | 
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